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ClinicalTrials.gov|Clinical Trial
Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies
Washington University School of Medicine
Abstract
This single arm pilot phase I study with safety run-in is designed to estimate the safety and efficacy of a familial mismatched or haploidentical hematopoietic stem cell transplantation (haplo-HSCT) using a novel graft modification technique (selective αβ-TCR and CD19 depletion). Phase: PHASE1 Status: RECRUITING Conditions: Pediatric Hematologic Malignancies Interventions: Ex Vivo T-cell receptor alpha-beta and CD19+ Depletion using CliniMACs Plus
Keywords
Pediatric Hematologic Malignancies