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Stem cell research & therapy|Peer-Reviewed
iPSC-derived exosomes promote diabetic wound healing by attenuating inflammatory responses.
Li Long, Ju Qiao, Liang Wang, Yue Wang, Yi Xu, Hui Chen, Hongzhong Jin, Wei He, Xiaohong Han, Jianmin Zhang
Abstract
Owing to impaired glucose metabolism, the high-glucose microenvironment in diabetic patients disrupts a series of biological reactions that hinder the wound healing process, resulting in a significant cost to the health care system and an urgent need for new and advanced therapies.
Keywords
<Keyword MajorTopicYN="N">ExosomesInduced pluripotent stem cellsInflammationRegenerationWound healing